منابع مشابه
Risk management profile of etoricoxib: an example of personalized medicine
The development of nonsteroidal anti-inflammatory drugs (NSAIDs) selective for cyclooxygenase (COX)-2 (named coxibs) has been driven by the aim of reducing the incidence of serious gastrointestinal (GI) adverse events associated with the administration of traditional (t) NSAIDs - mainly dependent on the inhibition of COX-1 in GI tract and platelets. However, their use has unravelled the importa...
متن کاملSafety of etoricoxib in patients with reactions to NSAIDs.
BACKGROUND Adverse reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) are a frequently reported problem due to the fact that these molecules are often used for control of pain and inflammation. Although the use of selective inhibitors of cyclooxygenase (COX) 2 helps to prevent some of these adverse reactions, they can have cardiac side effects when taken for prolonged periods. Here we r...
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Introduction Fluoroquinolones have demonstrated comparable efficacy and rates of adverse events as β-lactam and/or macrolide agents in the treatment of community-acquired and healthcare-associated infections. Fluoroquinolones currently marketed are generally considered to have good safety profiles (1–5). However, post-marketing spontaneous adverse event reports have imposed updates in the preca...
متن کاملContrast Agents: Safety Profile
Introduction Magnetic resonance contrast agents, in particular the gadolinium-based agents, are very safe and lack the nephrotoxicity (when injected intravenously) associated with iodinated contrast media. Minor adverse effects occur infrequently and include nausea, taste perversion, and hives. Whereas these agents cannot be differentiated on the basis of mild adverse effects, they do differ in...
متن کاملReassuring Safety Profile of Moxifloxacin
NOTE. Data from clinical trials are from [3]; data from postmarketing observationalstudies (PMOS) are on file. ADR, adverse drug reaction. Reprints or correspondence: Dr. Vladimir Krčmery, St. Elizabeth and University of Trnava Cancer Institute, Heyduková 10, 812 50 Bratislava, Slovak Republic ([email protected]). Clinical Infectious Diseases 2001; 32:1110–2 2001 by the Infectious Diseases Soci...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2002
ISSN: 0895-7061
DOI: 10.1016/s0895-7061(02)02315-4